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Fasudil br We did not make any assumptions regarding the mor
2020-08-04
We did not make any assumptions regarding the mortality Fasudil of mammography screening; instead, we predicted survival times using a Cox regression model that included age, tumor characteristics at diagnosis, and treatment. Covariate co-efficients on age, primary tumor size, and number of no
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br min at room temperature With the help
2020-08-03
15 min at room temperature. With the help of micro plate reader absorbance of the dye determined. Independent experiments were repeated at least three times to confirm the data. Quantification of the extracted dye was correlated with the live cell number. The percentage of viable cells in the c
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br The results are expected to provide experimental data and
2020-08-03
The results are expected to provide experimental data and a theoretical basis for the use of the anti-ovarian cancer agent apatinib in clinical practice. 2. Materials and methods Apatinib was obtained from Hengrui Medicine Co., Ltd. (Jiangsu, China). For the in vitro studies, apatinib was di
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br SK N SH neuroblastoma br No
2020-08-02
SK-N-SH, neuroblastoma No values DLD-1, colorectal cancer No values No values No values 2014; Liu and Zhou, 2017; Zhou et al., 2015). Possibly, 5,7-dimethoxy-4′-hydroxyflavanone and quercetin derivates played also a role in the tumor cell growth inhibition directly or by uphol
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br Methodology br Compound and cell lines br The
2020-08-02
2. Methodology 2.1. Compound and cell lines The compound 8-prenylnaringenin (Fig. 1A) was purchased from Santa Cruz Biotechnology, USA with molecular weight of 340.37 g/mol and purity > 98% (lot # A3014). Colon cancer (HCT-116) and normal colon (CCD-841) cell lines were purchased from ATCC,
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br Fig E ect of CAA on
2020-07-30
Fig. 9. Effect of CAA45 on autophagy in A549 cell. (A) Cells were plated on coverslips in 24-well plates, treated with CAA45 (0, 0.06, 0.12, 0.25 μM) or Rapa (0.30 μM) for 12 h, then stained with 0.05 mM MDC for 30 min at 37 °C. After washing with PBS, the stained A549 AZD7687 were immediately exam
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br MKI proliferation marker protein
2020-07-28
MKI67, proliferation marker protein Ki-67, is a nuclear protein ex-pressed in all proliferation vertebrate cells, and it is a widely biomarker to estimate the proportion of dividing cells to grade tumors [28,29]. Ki-67 expression is a late marker of Temozolomide entry and also is a central player
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D Chen X Zhuang J Zhai
2020-07-27
[9] D. Chen, X. Zhuang, J. Zhai, Y. Zheng, H. Lu, L. Chen, Preparation of highly sensitive Pt nanoparticles-carbon quantum dots/ionic liquid functionalized graphene oxide nanocomposites and application for H2 O2 detection, Sens. Actuators B-Chem. 255 (2018) 1500–1506. [11] X. Zhuang, D. Chen, S.
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br controlled study of dovitinib in
2020-07-26
controlled study of dovitinib in combination with fulvestrant in postmen-opausal patients with HR[+], HER2[−] breast cancer that Actinomycin D had progressed during or after prior endocrine therapy. Breast Cancer Res 2017 [pub-lished online]. [19] Finn RS, Crown JP, Lang I, et al. The cyclin-d
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br NC Untransduced cells OV AKT Cells transduced
2020-07-06
NC, Untransduced cells; OV AKT2, Cells transduced with pLVX-Neo-AKT2 lentivirus (AKT2-overexpressing cells); OV AKT2 hk2, Knocking out hk2 gene in AKT2-overexpressing cells; OV AKT2 hk2 + HK2T473A, The rescue of overexpressed HK2T473A mutants in AKT2-overexpressing HK2-deficient cells; OV AKT2 hk2
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br BBB physiological structure hBMVECs were
2020-07-06
BBB physiological structure. hBMVECs were cultured under a flu- idic shear of 0.1 ll/min, which was introduced by continuous per-fusion of cell culture medium on the vascular channel. To evaluate the BBB structure, we quantified TJ formation through permeation studies and protein analyses of th
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br Fig AR dependent stimulation of growth
2020-07-04
Fig. 5. AR-dependent stimulation of growth by adrenal androgens. (A) DHEAS and DHEA stimulated growth of VCaP cells. (B) DHEAS (DS) stimulated growth was diminished by AR antagonist bicalutamide (Bica) and STX64 (B). Cells were treated for 3 days and 7 days. Growth was assessed using MTT assay. D
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br Despite a lack of difference
2020-03-24
Despite a lack of difference in satisfaction between pa-tients engaging in active participation in decision-making and those who did not, the overwhelming patient-reported pref-erence for active participation and the strong influence that the doctor’s initial recommendation has on patient decision
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br Association studies br The
2020-03-17
2.3. Association studies The study comprised 507 cases and 560 controls. Primers and TaqMan probes were designed using the Primer Express software V2.0 (Applied Biosystems, Foster City, CA, USA) and procured from Applied Biosystems (Foster City, CA 94404, USA). Genotyping was accomplished by re
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br Accumulating evidence indicates that IRF negatively a
2019-11-11
Accumulating evidence indicates that IRF5 negatively affects the growth of many types of cancer cells. Thus, it was shown that ectopic expression of IRF5 reduced proliferation of chronic myeloid leukaemia Table 1 General characteristics of the NSCLC patients in this study. cells in vitro [