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br Similar to here we
2019-11-11
Similar to [5], here we assume no-flux of the cancer Selamectin or protease across the boundary of Ω. Therefore, the boundary conditions can be defined as the homogeneous Neumann boundary conditions The solution of the system (1a)–(1e) can then be uniquely determined using the boundary conditi
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br Baseline evaluation included a physical
2019-11-04
Baseline evaluation included a physical examination with digital rectal exam and performance status, pre-treatment PSA, assessment of baseline toxicity using Common Terminology Criteria for Adverse Events (CTCAE) version 4.0, and completion of the IPSS and EPIC-26 questionnaires.25 Treatment
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br ALDH enzymatic activity br ALDH enzyme in vitro
2019-10-30
ALDH enzymatic activity ALDH enzyme in vitro inhibition was assessed for each ALDHi as described (Morgan and Hurley, 2015). ALDHi (10 nm-20 mM,) were combined with propionaldehyde (200 mM) and NAD+ (100 mM) as substrates, and the increase in absorbance due to ALDH-mediated production of NADH wi
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br by mistakes in the characteristic qualities like
2019-10-29
by mistakes in the characteristic qualities like wrongly estimated factors, missing qualities while the latter is brought about by tests that are named to have a place in more than one class as well as misclassifica-tions. The computational cost increases with the increase in the di-mensionalit
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Heparin DL DOXt DOXf Total weight of NPs
2019-10-21
%DL = (DOXt – DOXf) /Total weight of NPs × 100% Chemical Engineering Journal 369 (2019) 134–149 where DOXt is the total amount of DOX used in the preparation of NPs and DOXf is the amount of unencapsulated DOX present in the super-natant. To evaluate DOX and OA release from [email protected]
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Tigecycline br Since CDDP did not induce cell
2019-10-21
Since CDDP did not induce cell death in AsPC-1 samples, caspase-dependency of apoptosis triggered with this compound was evaluated on MCF-7 cells only. Apoptotic death induced by the treatment with CDDP revealed as more caspase-dependent compared to that caused by 1, with very similar caspase-depe
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br The DM and EC genes
2019-10-16
The DM and EC Sevoflurane were then used for KEGG pathway enrichment analysis by the Fisher's exact test, using the size of the PPI network as background for the ECs and the number of genes with non-zero TDM scores for the DMs. Remarkably, while the DM genes are not significant-ly enriched with an
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br reported that CSCs are responsible for
2019-10-15
reported that CSCs are responsible for tumorigenesis, tumor main-tenance, metastasis and relapse. Moreover, these cells are characterized by their high resistance to chemotherapeutic drugs, radiotherapy and apoptosis and are considered as major factors of treatment failure (Luo et al., 2014). M
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br We also investigated the
2019-10-14
We also investigated the effect of CPT-11 alone or co-treatment of BP10A with CPT-11 on the growth of PDTX. As shown in Fig. 5A, treatment of CPT-11 alone inhibited the tumor growth at a less level as that of the tumor inhibitory activity caused by the BP10A or oxaliplatin treatment in all three PD
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br Figure AFL reverses cisplatin resistance
2019-10-14
Figure 6. AFL reverses cisplatin resistance in NSCLC. (A) Viability assays for A549 and H1299 Echinomycin treated with DMSO (control), cisplatin (10 μM) or cisplatin (10 μM) + AFL (25 μM). (B) Efficiency of Twist1 knockdown in A549 cells. ShCtrl denotes non-target scramble control. ShTwist1 #2
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br Some studies recommend dropping DCE altogether from mpMRI
2019-10-14
Some studies recommend dropping DCE altogether from mpMRI of the prostate (12,28 31). In PI-RADSv2, the role of DCE is minimized with readers simply evaluating for posi-tive enhancement or lack of enhancement, and its role in determining overall PI-RADS categorization is limited to equivocal PZ le
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b iframe width height src
2019-10-12
r> Acknowledgments We gratefully acknowledge the support of the National Sci-ence Foundation CAREER Award under Grant # CBET-1554018 and Flossie E. West Memorial Foundation Award. We thank medical on-cologists at Kansas Cancer Care Centers including Drs. Mark Fesen, Greg Nanney, Cinderella Chave
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br proportional hazards regression analysis on the training
2019-10-09
proportional hazards regression analysis on the training set to select and weight variables to be included in the novel LM molGPA. All prognostic factors were weighted for significance by statistical sig-nificance and hazard ratios (HR). The final index was chosen based on separation of prognostic
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br Input Training gene set D
2019-10-08
Input: Training gene set D, Number of genes s, Number of particles N, small constant . gravitational constantG0, Set of selected genes S, Global best accuracy achieved so far Gacc -so-far Output: Set of selected genes S, Global best accuracy Gacc 1. for each agent Si do 2. Randomly produce a
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br Statistical test br To statistically validate the perform
2019-10-02
4.6. Statistical test To statistically validate the performance of the proposed method, a Friedman test (Friedman, 1937) has been performed. The Friedman test validates the significance of ranking by utilizing an estimator FF to analyze the ranks of different methods on different datasets. Supp