• Garin Chesa P Old LJ Rettig WJ

  2019-10-02

  

  [21] Garin-Chesa P, Old LJ, Rettig WJ. Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers. Proc Nat Acad Sci USA 1990-Sep;87(18):7235–9. [22] Pure E, Blomberg R. Pro-tumorigenic roles of fibroblast activation protein in cancer: back

• projected to one dimension and the

  2019-09-27

  

  (projected to one dimension) and the algorithms are compared on sodium, digestible sugars, polysaccharides, vit A, vit B1, vit B12, the basis of this scalar metric. This only allows the comparison of the feature selector with respect to a reference: the random rank- • Other factors: fami

• br Cell cycle measurement br A and A DDP cells

  2019-09-24

  

  4.13. Cell cycle measurement A549 and A549/DDP cells were transferred into 6-well plates with a density of 10,000 per well, and cultured overnight at 37 °C. Then, 20 μM of the tested compounds were incubated with cells for 24 h. All adherent and floating cells were collected and washed twice wi

• br TME responsive biodegradable behavior

  2019-09-23

  

  2.2. TME-responsive biodegradable behavior of the nanoplatform As previously reported [27], MneO bonds can be destroyed by a high content of GSH and a weakly acidic environment, causing the release of Mn2+. Furthermore, there were abundant defects in the framework of MnSiO3, which could further

• br Fisher B Jeong JH Anderson S et

  2019-09-23

  

  11. Fisher B, Jeong JH, Anderson S, et al. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N Engl J Med 2002;347: 567-575. 13. White J. Defining target volumes in breast cancer GSK126 therapy for the

• br This is followed by the

  2019-09-23

  

  This is followed by the surgical procedure. In our patients, salvage surgery was started at a mean time of 19.7 h after injection of 99mTc-PSMA-I&S (range: 15.8–24.9 h). Patients were placed in a supine position and a urinary catheter was inserted. The latter allows removal of radioactive Dorsomor

• br Steroid hormones act through

  2019-09-16

  

  Steroid DETA NONOate act through both traditional and non-traditional receptors, which operate in parallel pathways and collaborate to exert the hormone's full effect [42]. Such a model exists in the case of 1α,25(OH)2D3; VDR and membrane-associated Pdia3 co-localize with the caveolae scaffolding pr

• br the combined treatments Fig S br Discussion br Strategies

  2019-09-16

  

  the combined treatments (Fig. S2). 4. Discussion Strategies designed to reverse acquired resistance to EGFR–TKIs are crucial to improve the prognosis of NSCLC patients. Autophagy has been demonstrated to confer the development of resistance to TKI treatment in NSCLC. Han et al. (2011) report

• br Cell binding assay br Saturation binding study

  2019-09-16

  

  2.6. Cell binding assay Saturation binding study was performed in MCF-7 E-64-c as described previously [26] to determine the binding affinity of [18F]FPTT for PR. Briefly, MCF-7 cells (approximately 2 × 105 cells/well) were incubated on a 24-well plate with [18F]FPTT, ranging from 1 nmol/L to 2

• br assignment RP vs EBRT Finally since estimation of

  2019-09-16

  

  248 assignment (RP vs. EBRT) (10). Finally, since estimation of life expectancy is rather difficult 249 and available prediction tools are suboptimal, clear strategies or suggestions on how to further ACCEPTED MANUSCRIPT 252 Conclusions 253 OCM rates at 5 years of follow-up were highes

• We next examined the most frequent co mutations in the

  2019-08-26

  

  We next examined the most frequent co-mutations in the two cohorts. In both the KEAP1/NFE2L2/CUL3 mutated and wildtype cohorts, TP53 was the most common mutation (75% and 50%, respectively). PIK3CA mutations occurred in 13% of the control cohort but did not appear in the KEAP1/NFE2L2/CUL3 mutated co

• br Materials and methods br Results In an extension to

  2019-08-16

  

  Materials and methods Results In an extension to our previous studies [6,11], we identified a population-based cohort of 2885 patients who were eligible for EGFR Solasodine testing. Of these patients, 184 (6.4%) were identified by death certificate or autopsy and excluded from further analysi

• br Conflict of interests br Author statement

  2019-08-16

  

  Conflict of interests Author statement Acknowledgments and Funding Information Drs. Arthur and Rohan are supported by a grant to Dr. Rohan from the Breast Cancer Research Foundation (BCRF-16-137). Introduction Colorectal cancer (CRC) is the third most common cancer in Europe [1]. With a

• Deregulation of PAKs activity has also been observed in

  2019-07-30

  

  Deregulation of PAKs activity has also been observed in HD (reviewed in [82]). HD is an autosomal dominant progressive ND that affects the basal ganglia (striatal neurons in the caudate nucleus and putamen) leading uncontrolled movements, emotional problems and loss of thinking ability (cognition).

• br Conclusions br Conflicts of interest br Transparency

  2019-07-30

  

  Conclusions Conflicts of interest Transparency document Transparency document The Transparency document associated with this article can be found, in online version. Introduction Alzheimer's disease (AD), as the most common neurodegenerative disorder, has been considered a leading ca

85 records 5/6 page Previous Next 12345 下5页 Last page